| Sep 8, 1pm | Home vs. Arizona |
| Sep 12, 8:15pm | at Miami |
| Sep 23, 7:30pm | Home vs. Jacksonville |
| Sep 29, 8:20pm | at Baltimore |
| Oct 6, 1pm | at Houston |
| Oct 14, 8:15pm | at New York Jets |
| Oct 20, 1pm | Home vs. Tennessee |
| Oct 27, 4:05pm | at Seattle |
| Nov 3, 1pm | Home vs. Miami |
| Nov 10, 1pm | at Indianapolis |
| Nov 17, 4:25pm | Home vs. Kansas City |
| Nov 24 | BYE |
| Dec 1, 8:20pm | Home vs. San Francisco |
| Dec 8, 4:25pm | at Los Angeles |
| Dec 15, 4:25pm | at Detroit |
| Dec 22, 1pm | Home vs. New England |
| Dec 29, 1pm | Home vs. New York Jets |
| TBD | at New England |
Buffalo Bills 2024 Football Schedule
Aug 23, 2024 | 1:07 PM